Infertility Medications

Texas IVF

1-866-IVF-Texas
1-866-483-8392

Gonadotropins (Gonal F, Follistim, Bravelle, Menopur, and Repronex)

These injectable medications are designed to stimulate the ovaries to produce follicles (fluid-filled sacs that contain developing eggs).

They contain FSH (follicle stimulating hormone) and/ or LH (luteinizing hormone). Dr. Rodriguez will evaluate all patients individually to determine the medication protocol that will best meet their individual needs. This is done by lab tests (blood and ultrasound) as well as a carefully acquired medical history and review of any previous treatment response/outcome, if applicable. During the treatment process, which typically is 8-11 days, patients are monitored frequently by ultrasound and blood tests, to assess their response. Dr. Rodriguez will adjust medication doses accordingly to promote the development of the follicles with the goal of providing quality oocytes (eggs) that hopefully will lead to a successful pregnancy.

These medications carry risks of side effects which include but are not limited to:

  • Ovarian Hyperstimulation Syndrome-OHSS- (approximately 2-5%). This is most likely to occur when there are a large number of follicles supported by a high serum estrogen level. Dr. Rodriguez will carefully consider options if this condition occurs and it is possible that the oocytes may be harvested but embryo transfer postponed to a later date OR the cycle may be cancelled altogether. OHSS symptoms may include sudden weight gain (3-5 pounds in a 24 hr period), extreme abdominal bloating and pain, dizziness, shortness of breath, and decreased urine output. The ovaries are very multi-cystic and changes in vascular permeability produces ascites (fluid) build-up and accumulation in the abdominal cavity. If not addressed and monitored carefully, this condition can cause imbalance in the electrolytes and in extremely rare instances, blood clots. It is very important that patients notify the nurse if experiencing any symptoms that may suggest this condition. OHSS is a “self-limiting” condition however, if pregnancy occurs, it may take up to 3-4 weeks to resolve. In extremely rare cases, surgical intervention is necessary because of ruptured cysts or ovarian torsion (twisting of the ovary cutting off blood supply) which may lead to loss of the ovary.
  • Multiple Gestation – (20-25%) – whenever gonadotropins are used to induce ovulation the possibility of multiples exist. With IUI, the incidence is higher because ovum pick-up cannot be controlled, With IVF, the goal is to produce a single, healthy baby and with the combined expertise of Dr. Rodriguez and the hospital's highly skilled embryology team, we are seeing a markedly reduced number of multiples in our practice and program overall.
  • Ectopic (Tubal) Pregnancy – (1-5%)
  • Ovarian Torsion(<1%)

Progesterone

Progesterone is a hormone that helps to ready the uterine environment for implantation or the early embryo. Progesterone can be administered intravaginal, oral or intramuscular route. Vaginal or oral capsules (100mg or 200mg) are taken 2 or 3 times daily; vaginal suppositories (25, 50 or 100mg) are inserted twice daily. The IM injection is 50 mg/cc. This injection is in a peanut oil base so please advise the nurses if you are allergic to nuts. The injection is given once daily, usually in the late afternoon. Side effects of progesterone may mimic premenstrual symptoms and include abdominal bloating, full breasts, and fatigue. The vaginal medications occasionally cause vaginal irritation.

Human Chorionic Gonadotropin (hCG)

Human chorionic gonadotropin (hCG) is required to ripen the follicles and make ovulation occur. this is available in intramuscular or subcutaneous form. Our practice prefers the brand Ovidrel which comes in a prefilled syringe and is administered subcutaneously. The hCG is similar to LH (luteinizing hormone) which induces ovulation. Ovidrel is given approximately 36 hours prior to egg retrieval or if intra-uterine insemination is being done, it is given in a similar time-frame based on the scheduling of the insemination.

Contact Info

6130 West Parker Road
Suite 215
Plano, TX 75093-8185

Telephone: 972-981-7800
1-866-IVF TEXAS
(1-866-483-8392)
Fax: 972-981-7814

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